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Product Description
Chorionic gonadotropin (CG) is produced by the trophoblastic cells of the placenta and stimulates the ovaries to release steroids essential for maintaining pregnancy. The four human glycoprotein hormones (CG, luteinizing hormone, follicle stimulating hormone, and thyroid stimulating hormone) are dimers consisting of alpha and beta subunits. The alpha subunits of these hormones are identical, while they each have unique beta subunits that allow the hormones to bind specific receptors on target cells to activate distinct downstream signaling pathways. The beta subunit of CG is encoded by six highly homologous genes which are arranged in tandem and inverted pairs on chromosome 19. Abnormalities in the CG beta subunit can cause ectopic pregnancy.
Biovision | P1714 | Human Chorionic Gonadotropin, β Subunit DataSheet
Biomolecule/Target :
Synonyms: Choriogonadotropin subunit beta; chorionic gonadotropin chain beta; CG-Beta; HCGB; CGB; HCG
Alternates names:
Taglines: Unique beta subunit of human chorionic gonadotropin; native protein isolated from human urine
NCBI Gene ID #: 93659
NCBI Gene Symbol:
Gene Source: Human
Accession #: P0DN86
Recombinant: False
Source: Human urine
Purity by SDS-PAGE: ≥ 95% by SDS-PAGE
Assay:
Purity:
Assay #2:
Endotoxin Level:
Activity (Specifications/test method): Activity verified by Accubind ELISA
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 22 kDa
Concentration:
Appearance: Lyophilized protein
Physical form description: Lyophilized powder
Reconstitution Instructions: Reconstitute using neutral pH buffer of choice. Avoid extreme high and low pH.
Amino acid sequence: Full length native protein (beta subunit only)
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
