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Product Description
PCNA (Proliferating Cell Nuclear Antigen) is found in the nucleus and is a cofactor of DNA polymerase delta. This protein is associated with DNA synthesis and repair. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. It appears during late G1- phase, Sphase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA may be induced by UV irradiation, growth factors and eventually by neighbouring tumours. Recombinant human PCNA, was expressed in E. coli and purified by conventional chromatography techniques.
Biovision | P1562 | PCNA, Human Recombinant DataSheet
Biomolecule/Target :
Synonyms: Proliferating cell nuclear antigen, MGC8367, Proliferating cell nuclear antigen, Proliferating cell nuclear antigen, PCNA
Alternates names: Proliferating cell nuclear antigen, MGC8367, Proliferating cell nuclear antigen, Proliferating cell nuclear antigen, PCNA
Taglines: A processivity factor for DNA polymerase δ
NCBI Gene ID #: 5111
NCBI Gene Symbol: PCNA
Gene Source: Human
Accession #: P12004
Recombinant: TRUE
Source: E. coli
Purity by SDS-PAGE: >95%
Assay: SDS - PAGE
Purity:
Assay #2:
Endotoxin Level:
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 28 kDa
Concentration:
Appearance: Liquid
Physical form description: Liquid
Reconstitution Instructions:
Amino acid sequence: aa 1-261
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
