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Product Description
PlGF-3 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-3 is expressed exclusively in the placenta. It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration. PlGF-3 lacks heparin binding affinity.--Recombinant Human PlGF-3 is a 45.7 kDa disulfide-linked homodimeric protein of two 203 amino acid polypeptide chains.
Biovision | P1563 | PLGF-3 Human Recombinant DataSheet
Biomolecule/Target :
Synonyms: PGFL, PLGF, PGF, Placenta growth factor
Alternates names: PGFL, PLGF, PGF, Placenta growth factor
Taglines: A key molecule in angiogenesis and vasculogenesis
NCBI Gene ID #: 5228
NCBI Gene Symbol: PGF
Gene Source: Human
Accession #: P49763
Recombinant: TRUE
Source: E. coli
Purity by SDS-PAGE: ≥ 95%
Assay: SDS - PAGE
Purity:
Assay #2:
Endotoxin Level: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)
Activity (Specifications/test method):
Biological activity: Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-50.0 ng/ml.
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 45.7 kDa
Concentration:
Appearance: Sterile Filtered colorless solution
Physical form description: Lyophilized
Reconstitution Instructions: Initially reconstitute in water to 0.1-1.0 mg/ml. Store at 2°C to 8°C for up to 1 week or prepare for extended storage.
Amino acid sequence: LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRHSPGRQS PDMPGDFRAD APSFLPPRRS LPMLFRMEWG CALTGSQSAV WPSSPVPEEI PRMHPGRNGK KQQRKPLREK MKPERCGDAV PRR
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
