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Product Description
SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant rat SDF-1α is a 7.9 kDa protein containing 68 amino acid residues.
Biovision | 7199 | SDF-1α/CXCL2, rat recombinant DataSheet
Biomolecule/Target :CXCL2
Synonyms: Stromal-Cell Derived Factor-1, CXCL12, PBSF
Alternates names: Stromal-Cell Derived Factor-1, CXCL12, PBSF
Taglines: Chemoattracts B and T cells and induces migration of CD34+ stem cells
NCBI Gene ID #: 24772
NCBI Gene Symbol: SDF-1
Gene Source: RAT
Accession #: Q9QZD1
Recombinant: Yes
Source: E. Coli
Purity by SDS-PAGE: ≥98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: < 0.1 ng/ug of protein (<1EU/ug).
Activity (Specifications/test method): Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50.0-100.0 ng/ml.
Biological activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50.0-100.0 ng/ml.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 7.9 kDa
Concentration: N/A
Appearance: Lyophilized powder
Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Amino acid sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNK
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
