Product Description
CYP2E1 polyclonal Antibody | AP0016 | Bioworld
Host: Rabbit
Reactivity: Human,Rat,Mouse
Application: WB
Application Range: WB: 1:1000~1:2000
Background: Cytochrome P450 2E1, metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CYP2E1 polyclonal Antibody detects endogenous levels of CYP2E1 protein.
Molecular Weight: ~ 55 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Cytochrome P450 2E1; 4-nitrophenol 2-hydroxylase; CYPIIE1; Cytochrome P450-J; CYP2E1; CYP2E
Immunogen: Synthetic peptide, corresponding to Human CYP2E1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Translational Contral elF4 and p70 S6 Kinase,Signaling Pathways Activating p38 MAP KinaseInhibition of Apoptosis,G Protein-coupled Receptors Signaling to MAPK Erk,Cell Cycle G2 M DNA Damage Signaling Pathway,Mitochondrial Control of Apoptosis,MTOR signaling,