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Product Description
HNF4α polyclonal Antibody | BS90653 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB ICC/IF IHC FC
Application Range: WB:1:1,000 ICC:1:50-1:200 IHC:1:100-1:500 FC:1:50-1:100
Background: HNF-4 alpha is a transcription factor that binds DNA as a homodimer. HNF-4 alpha is important in liver, kidney, and intestinal development. It has also been intensely studied as one of a variety of genes responsible for diabetes mellitus. HNF-4 alpha has been shown in knock out mice to be essential for the morphogenic and functional differentiation of hepatocytes. HNF-4 alpha is a dominant regulator of epithelial phenotypes able to drive the mesenchymal-to-epithelial transition when expressed in fibroblasts.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: HNF4α polyclonal Antibody detects endogenous levels of HNF4α protein.
Molecular Weight: 53 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: HNF-4-alpha, TCF-14, HNF4A, FLJ39654, FRTS4, Hepatic nuclear factor 4 alpha, Hepatocyte nuclear factor 4 alpha, Hepatocyte nuclear factor 4, Hepatocyte nuclear factor 4-alpha, HNF 4 alpha, HNF 4, HNF-4-alpha, HNF4, HNF4A, HNF4A, HNF4a7, HNF4a8, HNF4a9, Hnf4alpha, HNF4alpha10/11/12, MODY 1, MODY, MODY1, NR2A1, NR2A21, Nuclear receptor subfamily 2 group A member 1, OTTHUMP00000031060, OTTHUMP00000031062, TCF 14, TCF, TCF-14, TCF14, Tcf4, Transcription factor 14, hepatic nuclear factor, Transcription factor 14, Transcription factor HNF 4, Transcription factor HNF-4, Transcription factor HNF4,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway:
