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Product Description
MARK3 polyclonal Antibody | BS90825 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB IP ICC/IF IHC FC
Application Range: WB:1:500 IP:1:10-1:50 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background: MARK3 (MAP/microtubule affinity-regulating kinase 3), also known as C-TAK1 (Cdc25C-associated protein kinase 1), EMK-2 (ELKL motif kinase 2), protein kinase STK10 or serine/threonine-protein kinase p78, is a 753 amino acid peripheral membrane protein that phosphorylates Cdc25C on Serine 216 and is ubiquitously expressed in various human tissue and cell lines. Existing as six alternatively spliced isoforms, MARK3 belongs to the Ser/Thr protein kinase family and the protein kinase superfamily. MARK3 has been suggested to mediate the binding of the 14-3-3 proteins through its kinase activity and acts as a negative regulator of mitosis. The gene encoding MARK3 maps to human chromosome 14q32.3 and mouse chromosome 12 F1.
Storage & Stability: Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Specificity: MARK3 polyclonal Antibody detects endogenous levels of MARK3 protein.
Molecular Weight: 84 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: cTAK1, EMK-2, Par-1a, MARK3, CTAK1, EMK2, C-TAK1, Cdc25C associated protein kinase 1, Cdc25C-associated protein kinase 1, cTAK1, ELKL motif kinase 2, EMK-2, Emk2, ETK 1, KIAA4230, KP78, MAP microtubule affinity regulating kinase 3, MAP/microtubule affinity-regulating kinase 3, Mark3, MARK3, Par 1a, PAR1A, Protein kinase STK10, Ser/Thr protein kinase PAR-1, Serine threonine protein kinase p78, Serine/threonine-protein kinase p78, SerThr protein kinase PAR 1 Antibody
Immunogen: Recombinant protein within human Mark3 aa 600-750.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Protein A purified.
Pathway:
