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Product Description
XPO1 polyclonal Antibody | BS70045 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB
Application Range: WB 1:500 - 1:2000
Background: The protein encoded by this gene mediates leucine-rich nuclear export signal (NES) -dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: XPO1 polyclonal Antibody detects endogenous levels of XPO1 protein.
Molecular Weight: ~ 123 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CRM1; Exportin-1; Exportin 1; Exportin1; Exp1
Immunogen: A synthetic peptide of human XPO1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Inhibition of Apoptosis,
