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Product Description
Anti-MAPK1 (ERK2) monoclonal Antibody | MB62308 | Bioworld
Host: Mouse
Reactivity: Human, Monkey, Mouse, Rat, Dog
Application: IHC, IP, WB
Application Range: WB 1:2000, IHC 1:50, IP 2-4ug/mg
Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: mitogen-activated protein kinase 1
Molecular Weight: 41.4 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: ERK; ERK-2; ERK2; ERT1; MAPK2; p38; p40; p41; p41mapk; p42-MAPK; P42MAPK; PRKM1; PRKM2
Immunogen: Full length human recombinant protein of human MAPK1 (NP_620407) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
