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Product Description
Anti-NTRK3 (TrkC) monoclonal Antibody | MB62341 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IF, IHC, WB
Application Range: WB 1:1000 IHC 1:50 IF 1:100
Background: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: neurotrophic receptor tyrosine kinase 3
Molecular Weight: 94.4 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: GP145-TrkC; TRKC; gp145 (trkC)
Immunogen: Full-length protein expressed in 293T cell transfected with human NTRK3 expression vector
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
