Euro
USD
British Pound
NULL
Product Description
Anti-SSB monoclonal Antibody | MB62422 | Bioworld
Host: Mouse
Reactivity: Human, Monkey, Dog
Application: IF, IHC, IP, WB
Application Range: WB 1:1000~2000, IHC 1:150, IF 1:100, IP 2ug/500ul
Background: La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU (OH) elements of newly RNA polymerase III (see MIM 606007) -transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006 [PubMed 16387655]) .
Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: Sjogren syndrome antigen B
Molecular Weight: 46.8 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: La; La/SSB; LARP3
Immunogen: Full-length protein expressed in 293T cell transfected with human SSB expression vector
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
