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Product Description
Anti-USP5 monoclonal Antibody | MB62448 | Bioworld
Host: Mouse
Reactivity: Human, Monkey, Mouse, Rat, Dog
Application: IHC, WB
Application Range: WB 1:1000~2000, IHC 1:50
Background: Ubiquitin (see MIM 191339) -dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]) . [supplied by OMIM]
Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: ubiquitin specific peptidase 5
Molecular Weight: 93.1 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: ISOT
Immunogen: Full length human recombinant protein of human USP5 (NP_003472) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
