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Product Description
Anti-XRCC1 monoclonal Antibody | MB62451 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IF, IHC, WB
Application Range: WB 1:2000, IHC 1:50, IF 1:100
Background: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: X-ray repair complementing defective repair in Chinese hamster cells 1
Molecular Weight: 69.5 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: RCC
Immunogen: Full length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
