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Product Description
FGG monoclonal Antibody | MB63299 | Bioworld
Host: Mouse
Reactivity: Human, Monkey, Mouse
Application: IHC, WB
Application Range: WB 1:400~4000, IHC 1:150
Background: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: fibrinogen gamma chain
Molecular Weight: 46.4 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: fibrinogen; fibrinogen gamma chain; gamma chain; gamma polypeptide
Immunogen: Full length human recombinant protein of human FGG (NP_000500) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
