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Product Description
FSCN1 monoclonal Antibody | MB63341 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IHC, WB
Application Range: WB 1:500, IHC 1:500
Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: fascin actin-bundling protein 1
Molecular Weight: 54.3 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: FAN1; HSN; p55; SNL
Immunogen: Full length human recombinant protein of human FSCN1 (NP_003079) produced in HEK293T.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
