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Product Description
JUP monoclonal Antibody | MB63696 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IHC, WB
Application Range: WB 1:500, IHC 1:2000
Background: This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: junction plakoglobin
Molecular Weight: 81.6 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: ARVD12; CTNNG; DP3; DPIII; PDGB; PKGB
Immunogen: Human recombinant protein fragment corresponding to amino acids 500-745 of human JUP (NP_002221) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
