Product Description
MAK monoclonal Antibody | MB63885 | Bioworld
Host: Mouse
Reactivity: Human, Rat
Application: IHC, WB
Application Range: WB 1:500~2000, IHC 1:150
Background: The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: male germ cell associated kinase
Molecular Weight: 70.5 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: dJ417M14.2; RP62
Immunogen: Human recombinant protein fragment corresponding to amino acids 291-623 of human MAK (NP_005897) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A