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Product Description
NEFH monoclonal Antibody | MB64164 | Bioworld
Host: Mouse
Reactivity: Human, Rat
Application: IHC, WB
Application Range: WB 1:2000, IHC 1:2000
Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: neurofilament, heavy polypeptide
Molecular Weight: 112.4 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CMT2CC; NFH
Immunogen: Human recombinant protein fragment corresponding to amino acids 778-1020 of human NEFH (NP_066554) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
