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Product Description
NR4A3 monoclonal Antibody | MB64252 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IHC, WB
Application Range: WB 1:2000, IHC 1:150
Background: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE) . Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15) . Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: nuclear receptor subfamily 4 group A member 3
Molecular Weight: 68 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CHN; CSMF; MINOR; NOR1; TEC
Immunogen: Human recombinant protein fragment corresponding to amino acids 332-626 of human NR4A3 (NP_008912) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
