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Product Description
PSMA2 (Proteasome 20S alpha 2) monoclonal Antibody | MB64656 | Bioworld
Host: Mouse
Reactivity: Human, Monkey, Mouse, Rat, Dog
Application: IHC, WB
Application Range: WB 1:2000, IHC 1:500
Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq, Jul 2008]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: proteasome subunit alpha 2
Molecular Weight: 25.7 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: HC3; MU; PMSA2; PSC2
Immunogen: Human recombinant protein fragment corresponding to amino acids 50-234 of human PSMA2 (NP_002778) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
