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Product Description
PTPN7 (HePTP) monoclonal Antibody | MB64718 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IF, IHC, WB
Application Range: WB 1:2000, IHC 1:150, IF 1:100
Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: protein tyrosine phosphatase non-receptor type 7
Molecular Weight: 44.8 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI
Immunogen: Full length human recombinant protein of human PTPN7 (NP_542155) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
