Product Description
TCAP monoclonal Antibody | MB65355 | Bioworld
Host: Mouse
Reactivity: Human, Mouse
Application: IHC, WB
Application Range: WB 1:2000, IHC 1:150
Background: Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: titin-cap
Molecular Weight: 18.9 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CMD1N; CMH25; LGMD2G; T-cap; TELE; telethonin
Immunogen: Full length human recombinant protein of human TCAP (NP_003664) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A