Product Description
RHO polyclonal Antibody | BS64057 | Bioworld
Host: Rabbit
Reactivity: Human,Rat,Mouse
Application: WB
Application Range: WB: 1:1000~1:2000
Background: Rhodopsin is the photoreceptor in the retinal rods. It is activated by photons, transduces visual information through its cognate G protein, transducin, and is inactivated by arrestin binding. Using atomic-force microscopy, rhodopsin was found to be arranged into paracrystalline arrays of dimers in mouse disc membranes. Rhodopsin is considered to be the prototype of G protein-coupled receptors (GPCRs), and is the first GPCR for which a crystal structure was solved. Research studies have linked mutations in the gene encoding rhodopsin to retinitis pigmentosa, a disease characterized by retinal degeneration resulting in reduced peripheral vision and night blindness.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: RHO polyclonal Antibody detects endogenous levels of RHO protein.
Molecular Weight: ~ 37, 75, 150 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Rhodopsin; Opsin-2; RHO; OPN2
Immunogen: Synthetic peptide, corresponding to Human RHO.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: