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Product Description
Syntrophin α1 polyclonal Antibody | BS91311 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse
Application: WB ICC IF IHC FC
Application Range: WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:200
Background: The syntrophins are PDZ-domain-containing proteins that facilitate the recruitment of signaling proteins such as NOS1 to the dystrophin-associated protein complex. The syntrophin family are structurally related proteins that contain multiple protein interaction motifs. Syntrophins associate directly with dystrophin, the product of the Duchenne muscular dystrophy locus, and its homologs. α-Syntrophin has an important role in synapse formation and in the organization of utrophin, acetylcholine receptor and acetylcholinester-ase at the neuromuscular synapse. Specifically, NOS1 binds to α-Syntrophin at muscle sarcolemma. β2-Syntrophin is a modular adapter. In muscle cells, β2-Syntrophin interacts with members of the dystrophin family, which in-cludes utrophin.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: Syntrophin α1 polyclonal Antibody detects endogenous levels of Syntrophin α1 protein.
Molecular Weight: 54 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: TACIP1, SNTA1, SNT1, 59 kDa dystrophin-associated protein A1 acidic component 1, Acidic alpha 1 syntrophin, Alpha 1 syntrophin, Alpha-1-syntrophin, dJ1187J4.5, Dystrophin associated protein A1 59kDa acidic component, LQT12, OTTHUMP00000030650, Pro-TGF-alpha cytoplasmic domain-interacting protein 1, SNT1, Snta1, SNTA1, Syntrophin 1, Syntrophin-1, TACIP1,
Immunogen: Recombinant protein within human Syntrophin alpha 1 aa 1-200.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway:
