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Product Description
ADORA1 (D326) polyclonal Antibody | BS2780 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: IHC IF
Application Range: IHC: 1:50~1:200 IF: 1:50~1:200
Background: Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ADORA1 (D326) polyclonal Antibody detects endogenous levels of Adenosine receptor A1 protein.
Molecular Weight: ~ 37 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Adenosine receptor A1; Adenosine A1-R
Immunogen: Synthetic peptide, corresponding to amino acids 300-345 of Human ADORA1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
