Product Description
ART1 Polyclonal Antibody | BS65729 | Bioworld
Host: Rabbit
Reactivity: Human,
Application: IHC-P,
Application Range: IHC-P=1:100-500
Background: Phemx is a member of the tetraspanin (TM4SF) family of proteins that may be involved in transmembrane signal transduction, regulation of cell proliferation, differentiation and motility. Phemx is a multi-pass membrane protein containing intracellular N- and C-terminal domains, four transmembrane domains and two extracellular loops. It is ubiquitously expressed from early embryogenesis through adulthood. Phemx exhibits predominant expression in hematopoietic tissues suggesting a role in hematopoietic-cell function. In association with the Integrin αIIb/Integrin β3 complex, Phemx functions to stabilize arterial thrombi in platelets and regulate “outside-in” signaling. This interaction may be important in the process of wound healing. The gene encoding Phemx is located in an important tumor-suppressor gene region that has been associated with Beckwith-Wiedemann syndrome as well as a variety of cancers
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ART1 Polyclonal Antibody detects endogenous levels of ART1 protein.
Molecular Weight: 35kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: ART 1; ART1; FLJ17158; FLJ97586; MGC22455; Pan hematopoietic expression; PHEMX; PHMX; tetraspanin 32; Tetraspanin; tetraspanin32; TSPAN32; TSSC6; Tumor suppressing STF cDNA 6; Tumor suppressing subchromosomal transferable fragment cDNA 6; Tumor suppressing subtransferable candidate 6.
Immunogen: KLH conjugated synthetic peptide derived from human PHEMX/ART1:101-200/320
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: affinity purified by Protein A
Pathway: