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Product Description
Cathepsin E (I292) polyclonal Antibody | BS3446 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: IHC
Application Range: IHC: 1:50~1:200
Background: Cathepsin E is an intracellular aspartic protease of the pepsin family, which is structurally highly homologous to the lysosomal aspartic protease cathepsin D. Cathepsin E is less abundant than Cathepsin D and has a more limited distribution, which includes lymphoid tissues, gastrointestinal tract tissue, blood cells, microglia and activated B lymphocytes. It is not expressed in resting B lymphocytes.Cathepsin E may have a role in immune function. It is most likely involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. It may also play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Cathepsin E (I292) polyclonal Antibody detects endogenous levels of Cathepsin E protein.
Molecular Weight: ~ 48 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Cathepsin E; CTSE
Immunogen: Synthetic peptide, corresponding to amino acids 260-310 of Human Cathepsin E.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
