Euro
USD
British Pound
NULL
Product Description
DDIT3 polyclonal Antibody | BS90400 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse
Application: WB FC
Application Range: WB:1:500-1:2,000 FC:1:50-1:100
Background: DDIT3 also named GADD 153 which has been described as a growth arrest and DNA damage-inducible gene that encodes a C/EBP-related nuclear protein. This protein has also been designated C/EBP-homologous protein (CHOP-10) . GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase in cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD 153 dimers away from "classical" C/EBP binding sites, recognizing instead unique "nonclassical" sites. Thus GADD 153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells, similar to the regulatory function of Id on the activity of Myo D and Myo D-related proteins involved in the development of muscle cells.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: DDIT3 polyclonal Antibody detects endogenous levels of DDIT3 protein.
Molecular Weight: 27 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: DDIT-3, CHOP, CHOP-10, DDIT3, CHOP, CHOP10, GADD153, C/EBP homologous protein, C/EBP Homology Protein, C/EBP zeta, C/EBP-homologous protein 10, C/EBP-homologous protein, CCAAT/enhancer binding protein homologous protein, CEBPZ, CHOP 10, CHOP, CHOP-10, CHOP10, DDIT 3, DDIT-3, Ddit3, DDIT3, DNA Damage Inducible Transcript 3, DNA damage-inducible transcript 3 protein, GADD 153, GADD153, Growth Arrest and DNA Damage Inducible Protein 153, Growth arrest and DNA damage inducible protein GADD153, Growth arrest and DNA damage-inducible protein GADD153, MGC4154,
Immunogen: Synthetic peptide within human DDIT3 aa 70-110.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Peptide affinity purified.
Pathway:
