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Product Description
Dynamin 2 polyclonal Antibody | BS90433 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB ICC/IF IHC FC
Application Range: WB:1:500-1:1,000 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:50-1:100
Background: Members of the dynamin family, including Dynamin I and Dynamin II, are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression found in testis. Both dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the dynamins and effectors of their GTPase activity. The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to clathrin coated pits by SH3 domain interaction with amphiphysin, a protein highly expressed in brain.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Dynamin 2 polyclonal Antibody detects endogenous levels of Dynamin 2 protein.
Molecular Weight: 98 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: DNM2, DYN2, CMT2M, CMTDI1, CMTDIB, DI CMTB, Dnm2, DYN II, DYN2, DYN2, Dynamin II, Dynamin-2, Dynamin2, DynaminII, DYNII,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway:
