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Product Description
GUF1 polyclonal Antibody | BS65163 | Bioworld
Host: Rabbit
Reactivity: Human
Application: IHC-p,IF (paraffin section),ELISA
Application Range: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Background: GUF1 homolog, GTPase (GUF1) Homo sapiens This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GUF1 Polyclonal Antibody detects endogenous levels of GUF1 protein.
Molecular Weight: /
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: GUF1; Translation factor GUF1; mitochondrial; Elongation factor 4 homolog; EF-4; GTPase GUF1; Ribosomal back-translocase
Immunogen: The antiserum was produced against synthesized peptide derived from human GUF1. AA range:421-470
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pathway:
