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Product Description
HARS polyclonal Antibody | BS72950 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB
Application Range: WB 1:500 - 1:2000
Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: HARS polyclonal Antibody detects endogenous levels of HARS protein.
Molecular Weight: 57kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CMT2W;HRS;USH3B
Immunogen: Recombinant protein of human HARS
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
