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Product Description
Hemogen Polyclonal Antibody | BS65720 | Bioworld
Host: Rabbit
Reactivity: Human,
Application: FCM,
Application Range: Flow-Cyt=1ug/test
Background: Hemogen is a 484 amino acid protein encoded by the human gene HEMGN. Hemogen is a nuclear protein that is expressed in hematopoietic precursor cells and can be detected in CD34+ and K-562 leukemia cell line. It is also expressed in bone marrow, testis, thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. Hemogen is down-regulated during megakaryocytic differentiation of K-562 cells by 12-O-tetradecanoylphorbol-13-acetate (TPA) (at protein level) . It can be up-regulated in normal PBMCs by mitogens.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Hemogen Polyclonal Antibody detects endogenous levels of Hemogen protein.
Molecular Weight: 55kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: EDAG; EDAG-1; Erythroid differentiation-associated gene protein; HEMGN; HEMGN_HUMAN; Hemogen; Hemopoietic gene protein; Negative differentiation regulator protein.
Immunogen: KLH conjugated synthetic peptide derived from human Hemogen/EDAG:51-150/484
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: affinity purified by Protein A
Pathway:
