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Product Description
IFI-16 (N772) polyclonal Antibody | BS3865 | Bioworld
Host: Rabbit
Reactivity: Human
Application: IHC
Application Range: IHC: 1:50~1:200
Background: Interferon-gamma inducible protein 16 (IFI16) belongs to the HIN-200 family of transcriptional regulator linked to cell cycle regulation and differentiation by modulating the activities of multiple transcriptional factors, such as p53 and Rb. The HIN-200 (hematopoeitic interferon-inducible nuclear antigens with 200 amino acid repeat) family members contain a DNA binding domain, a transcriptional regulatory domain, DAPIN/PAAD domain associated with interferon response and a binding domain for BRCA1. IFI16 may have a role in the regulation of hematopoeitic cell differentiation and also be involved in DNA repair since it becomes a component of the DNA repair multi-protein BASC complex after UV-induced DNA damage. IFI16 is strongly induced by gamma interferon in vivo.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IFI-16 (N772) polyclonal Antibody detects endogenous levels of IFI-16 protein.
Molecular Weight: ~ 88 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Gamma-interferon-inducible protein Ifi-16; Interferon-inducible myeloid differentiation transcriptional activator; IFI16; IFNGIP1
Immunogen: Synthetic peptide, corresponding to amino acids 740-795 of Human IFI-16.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
