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Product Description
NFkB-p65 (phospho-S468) polyclonal Antibody | BS4136 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: IHC IP
Application Range: IHC: 1:50~1:200 IP: 1:50~1:200
Background: p65 is a subunit of the nuclear factor kappa B. The transcription factor NFkB is widely recognized as a critical mediator of immune and inflammatory responses. In most cell types, NFkB is found in the cytoplasm where it is associated with an inhibitory prd in many tissues. A high proportion of spontaneous NIH/3T3 transformants overexpress c-Met and by transfection analysis the c-Met proto-oncogene has been shown to exhibittransforming activity.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: p-NFκB-p65 (S468) polyclonal Antibody detects endogenous levels of NFκB-p65 protein when phosphorylated at Ser468.
Molecular Weight: ~ 60, 75 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: p65; p65 NF kappaB; p65 NFkB; RELA; NFKB P65; Transcription Factor p65; Nuclear factor NF-kappa-B p65 subunit; NFkB-p65; NFKB3
Immunogen: Synthetic phosphopeptide derived from human NFkB-p65 around the phosphorylation site of Serine 468.
Conjugate: Unconjugated
Modification: Phosphorylation
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: NF-kB Signaling,NF-kB Signaling,Immune Cell Signaling,Signaling Pathways Activating p38 MAP KinaseSTING Signaling,T cell receptor signaling,Inhibition of Apoptosis,Contribution of Soluble Factors to EMT,
