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Product Description
phospho-NeuroD1 (Ser274) Polyclonal Antibody | BS65833 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat,Pig,Cow,Sheep,
Application: IHC-P,
Application Range: IHC-P=1:100-500
Background: This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008]
Storage & Stability: Store at 4°C short term. Aliquot and store at -6°C long term. Avoid freeze-thaw cycles.
Specificity: phospho-NeuroD1 (Ser274) Polyclonal Antibody detects endogenous levels of NeuroD1 protein only when phosphorylated at Y274.
Molecular Weight: ~40 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: NeuroD1 (phospho S274) ; p-NeuroD1 (phospho S274) ; atonal; basic helix loop helix transcription factor; BETA 2; Beta cell E box transactivator 2; BETA2; BHF 1; BHF1; bHLHa3; class A basic helix loop helix protein 3; Class A basic helix-loop-helix protein 3; MODY 6; MODY6; NDF1_HUMAN; NEUROD; NeuroD1; Neurogenic differentiation 1; Neurogenic differentiation factor 1; neurogenic helix loop helix protein NEUROD; NIDDM
Immunogen: KLH conjugated Synthesised acetylpeptide derived from human NeuroD1 around the acetylation site of Ser274:PL (p-S) PP
Conjugate: Unconjugated
Modification: Phosphorylation
Purification & Purity: affinity purified by Protein A
Pathway:
