Product Description
YARS polyclonal Antibody | BS8444 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB 1:500 - 1:2000
Background: Tryptophanyl-tRNA synthetases are essential enzymes that catalyze the aminoacylation of tRNA (Trp) with tryptophan, an essential function of the cell’s protein synthesis machinery. Two forms of tryptophanyl-tRNA synthetase exist; a cytoplasmic form, named TrpRS (also known as WARS), and a mitochondrial form, named WARS2. In normal cells, human TrpRS exists as a full length form and as a truncated form designated mini TrpRS, which is produced by alternative splicing. Expression of mini TrpRS is highly stimulated in human cells by the addition of IFN-g. Although both human full length TrpRS and mini TrpRS are enzymatically active in aminoacylation, they differ in angiostatic activity. The tyrosyl-tRNA synthetase (TyrRS), a protein related to TrpRS, exists as a homodimeric enzyme that catalyzes the aminoacylation of tRNA (Tyr) by L-tyrosine.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: YARS polyclonal Antibody detects endogenous levels of YARS protein.
Molecular Weight: ~ 59 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Tyrosine--tRNA ligase, cytoplasmic; Tyrosyl-tRNA synthetase; TyrRS; YARS
Immunogen: Recombinant full length Human YARS.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: