Euro
USD
British Pound
NULL
Product Description
PDE4B monoclonal Antibody | MB64411 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: FC, IHC, WB
Application Range: WB 1:500~2000, IHC 1:150, FLOW 1:100
Background: This gene is a member of the type IV, cyclic AMP (cAMP) -specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: phosphodiesterase 4B
Molecular Weight: 83.2 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: DPDE4; PDE4B5; PDEIVB
Immunogen: Full length human recombinant protein of human PDE4B (NP_002591) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
