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Product Description
RASGRP3 monoclonal Antibody | MB64843 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: WB
Application Range: WB 1:2000
Background: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]) . [supplied by OMIM, Mar 2008]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: RAS guanyl releasing protein 3
Molecular Weight: 78.2 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: GRP3
Immunogen: Human recombinant protein fragment corresponding to amino acids 380-690 of human RASGRP3 (NP_733772) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
