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Product Description
Contactin-2 polyclonal Antibody | BS5672 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig) -like and four Fibronectin type III (FNIII) -like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding) . The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Contactin-2 polyclonal Antibody detects endogenous levels of Contactin-2 protein.
Molecular Weight: ~ 135 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Contactin 2; Contactin2; xonal glycoprotein TAG-1; Axonin-1; Axonin 1; Axonin1; Transient axonal glycoprotein 1; TAX-1; CNTN2; AXT; TAG1; TAX1
Immunogen: Synthetic peptide, corresponding to amino acids 157-202 of Human Contactin-2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
