Product Description
CPB2 polyclonal Antibody | BS65256 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB,ELISA
Application Range: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Background: carboxypeptidase B2 (CPB2) Homo sapiens Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues) . The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TAFI Polyclonal Antibody detects endogenous levels of TAFI protein.
Molecular Weight: ~ 48 kDa
Note: For
Alternative Names: CPB2; Carboxypeptidase B2; Carboxypeptidase U; CPU; Plasma carboxypeptidase B; pCPB; Thrombin-activable fibrinolysis inhibitor; TAFI
Immunogen: The antiserum was produced against synthesized peptide derived from human CPB2. AA range:321-370
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pathway: