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Product Description
cTnI (Phospho-S22/S23) polyclonal Antibody | BS64505 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC) . Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: cTnI (Phospho-S22/S23) polyclonal Antibody detects endogenous levels of cTnI protein only when phosphorylated at Ser22/Ser23.
Molecular Weight: ~ 28 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Troponin I, cardiac muscle; Cardiac troponin I; TNNI3; TNNC1
Immunogen: Synthetic phosphopeptide derived from human cTnI around the phosphorylation site of Serine 22/Serine 23.
Conjugate: Unconjugated
Modification: Phosphorylation
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Phosphoinosotode Signaling,Protein Kinase C Signaling,Immune Cell Signaling,Warburg Effect,Insulin &Glucose Signaling,ErbB HER Signaling,
