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Product Description
GPR142 polyclonal Antibody | BS62386 | Bioworld
Host: Rabbit
Reactivity: Human,Rat,Mouse
Application: WB IHC
Application Range: WB: 1:500~1000
Background: Gas8 (growth arrest-specific 8), also known as Gas11, is a 478 amino acid protein that localizes to the Golgi apparatus, as well as to the cytoplasm and the flagellar basal body, and belongs to the growth arrest-specific protein family. Expressed in liver, heart and skeletal muscle with lower levels present in lung, brain, kidney and placenta, Gas8 functions as a cytoskeletal linker that binds microtubules and is thought to play a role in axonemal and non-axonemal dynein regulation. Gas8 may also be involved in spermatozoa motility and, when defective, may be associated with infertility in males lacking gametocytes. The gene encoding Gas8 maps to a region on human chromosome 16 that is frequently deleted in breast and prostate cancer, suggesting a role for Gas8 in tumorigenesis.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GAS8 polyclonal Antibody detects endogenous levels of GAS8 protein.
Molecular Weight: ~ 56 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Dynein regulatory complex subunit 4; Growth arrest-specific protein 11; GAS-11; Growth arrest-specific protein 8; GAS-8; GAS8; DRC4;GAS11
Immunogen: Synthetic peptide, corresponding to Human GAS8.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .
Pathway:
