Euro
USD
British Pound
NULL
Product Description
GPR146 polyclonal Antibody | BS62390 | Bioworld
Host: Rabbit
Reactivity: Human,Rat,Mouse
Application: WB IHC
Application Range: WB: 1:500~1000
Background: Msx homeobox genes encode for transcription factors that control morphogenesis and are expressed at sites of epithelial-mesenchymal interaction during embryogenesis, such as the Tooth. Two of these genes, Msx-1 and Msx-2, are key factors for the development of tooth and craniofacial skeleton. Msx-1 also down-regulates a master gene of skeletal cells differentiation. Msx-1 and Msx-2 contribute to the initial patterning of dentition as well as playing a pivotal role in terminal cell differentiation. In addition, Msx-1 and Msx-2 are expressed in the epidermis, hair follicles and fibroblasts of the developing fetal skin. In adult skin, Msx-1 and Msx-2 expression is confined to epithelially derived structures. Msx-2 is detected as a diffuse cytoplasmic signal in fetal epidermis and portions of the hair follicle and dermis, but is localized to the nucleus in the adult epidermis. Msx-1 and Msx-2 are also expressed during critical developmental stages of neural tube and neuralcrest, suggesting that these genes play an important role in organogenesis.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MSX2 polyclonal Antibody detects endogenous levels of MSX2 protein.
Molecular Weight: ~ 34 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Homeobox protein MSX-2; Homeobox protein Hox-8; MSX2; HOX8
Immunogen: Synthetic peptide, corresponding to Human MSX2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .
Pathway:
