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Product Description
HKR1 (W154) polyclonal Antibody | BS1923 | Bioworld
Host: Rabbit
Reactivity: Humam
Application: WB IHC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HKR1, also known as Krueppel-related zinc finger protein 1 or zinc finger protein 875, is a 659 amino acid nuclear protein that is thought to play a role in transcriptional regulation. Existing as two alternatively spliced isoforms, HKR1 is a member of the Krueppel C2H2-type zinc-finger protein family and contains thirteen C2H2-type zinc fingers and one KRAB domain. The gene encoding HKR1 maps to human chromosome 19q13.12.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: HKR1 (W154) polyclonal Antibody detects endogenous levels of HKR1 protein.
Molecular Weight: ~ 73 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Krueppel-related zinc finger protein 1; Protein HKR1; Zinc finger protein 875; HKR1; ZNF875
Immunogen: Synthetic peptide, corresponding to amino acids 111-160 of Human HKR1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
