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Product Description
IL17RD polyclonal Antibody | BS70687 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB 1:500 - 1:2000
Background: Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons (By similarity) .
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IL17RD polyclonal Antibody detects endogenous levels of IL17RD protein.
Molecular Weight: ~ 110 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Interleukin-17 receptor D; IL-17 receptor D; IL17Rhom; Interleukin-17 receptor-like protein; Sef homolog; hSef; IL17RD; IL17RLM; SEF; UNQ6115/PRO20026
Immunogen: Recombinant protein of human IL17RD.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
