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Product Description
LARP1 polyclonal Antibody | BS71974 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB
Application Range: WB 1:500 - 1:2000
Background: La-related protein 1 (LARP1), also known as KIAA0731, is a 1,096 amino acid protein belonging to the LARP family. LARP1 contains two conserved regions, one that shares homology with La/SSB proteins and one that is conserved only across LARP family proteins. Within the La/SSB conserved region, LARP1 contains a HTH La-type RNA-binding domain, which may indicate a role in RNA stabalization and folding. Upon DNA damage, LARP1 is phosphorylated by ATR or ATM. LARP1 interacts with many signaling intermediate proteins, including 14-3-3 β, 14-3-3 γ, 14-3-3 θ and 14-3-3 . Widely expressed, LARP1 levels are highest in heart. LARP1 exists as three isoforms produced by alternative splicing.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: LARP1 polyclonal Antibody detects endogenous levels of LARP1 protein.
Molecular Weight: 163kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: LARP; La-related protein 1; KIAA0731
Immunogen: Recombinant Protein of human LARP1
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
