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Product Description
MT-ND3 polyclonal Antibody | BS60188 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB
Application Range: WB: 1:500~1:1000
Background: NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MT-ND3 polyclonal Antibody detects endogenous levels of MT-ND3 protein.
Molecular Weight: ~ 13 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: NADH-ubiquinone oxidoreductase chain 3 ; EC=1.6.5.3; NADH dehydrogenase subunit 3; MT-ND3; MTND3; NADH3; ND3
Immunogen: A synthetic peptide corresponding to residues in Human MT-ND3.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
