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Product Description
NUB1 (Y601) polyclonal Antibody | BS1464 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC IP
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200 IP: 1:10~1:100
Background: NEDD8 is a ubiquitin-like protein that controls vital biological events through its conjugation to cullin proteins. NEDD8 ultimate buster-1 (NUB1), is a negative regulator of the NEDD8 system that recruits NEDD8 and its conjugates to the proteasome for degradation. It is, therefore a cell growth regulator. The UBA domain of NUB1 is the specific acceptor for the linear ubiquitin precursor. NUB1 is composed of 601 amino acids. It is an interferon-inducible protein and predominantly localizes in the nucleus. NUB1 is specifically expressed in adult human testis, ovary, heart, and skeletal muscle tissues.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NUB1 (Y601) polyclonal Antibody detects endogenous levels of NUB1 protein.
Molecular Weight: ~ 70 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: NEDD8 ultimate buster 1; Negative regulator of ubiquitin-like proteins 1; Renal carcinoma antigen NY-REN-18; NUB1; NYREN18
Immunogen: Synthetic peptide, corresponding to amino acids 570-621 of Human NUB1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Jak Stat ：IL-6 Receptor Signaling,Examples of Crosstalk Between Post-translational Modifications,
