Euro
USD
British Pound
NULL
Product Description
PER1 polyclonal Antibody | BS71237 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB IHC IF
Application Range: WB: 1:500 - 1:2000 IHC: 1:50 - 1:100 IF: 1:50 - 1:200
Background: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PER1 polyclonal Antibody detects endogenous levels of PER1 protein.
Molecular Weight: ~ 50 KDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: PER1;PER;RIGUI;Hper
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PER1 (NP_002607.2) .
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: N/A
