Product Description
PTPR2 polyclonal Antibody | BS65287 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
Application Range: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Background: protein tyrosine phosphatase, receptor type N2 (PTPRN2) Homo sapiens This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PTP IA-2β Polyclonal Antibody detects endogenous levels of PTP IA-2β protein.
Molecular Weight: ~ 111 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: PTPRN2; KIAA0387; Receptor-type tyrosine-protein phosphatase N2; R-PTP-N2; Islet cell autoantigen-related protein; IAR; ICAAR; Phogrin
Immunogen: The antiserum was produced against synthesized peptide derived from human PTPRN2. AA range:206-255
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pathway: